BDA-366

Cat. No.: IBDI-437122

BDA-366 is a potent Bcl2 antagonist (Ki = 3.3 nM), binding Bcl2-BH4 domain with high affinity and selectivity. BDA-366 induces conformational change in Bcl2 that abrogates its antIAP; optotic function, converting it from a survival molecule to a cell death inducer. BDA-366 suppresses growth of lung cancer cells.

Product Details

Target	Bcl-2 Family
Molecular Weight	423.50
SMILES	O=C1C2=C(C(NC[[email protected]]3CO3)=CC=C2NC[[email protected]](O)CN(CC)CC)C(C4=CC=CC=C41)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.