Belzutifan

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Cat. No.: IBDI-434237

Belzutifan (PT2977) is an orally active and selective HIF-2α inhibitor with an IC50 of 9 nM. Belzutifan, as a second-generation HIF-2α inhibitor, increases potency and improves pharmacokinetic profile. Belzutifan is a potential treatment for clear cell renal cell carcinoma (ccRCC).

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	HIF/HIF Prolyl-Hydroxylase
Molecular Weight	383.34
Appearance	Solid
Synonyms	PT2977, MK-6482
SMILES	N#CC1=CC(F)=CC(OC2=CC=C(S(=O)(C)=O)C3=C2[[email protected]@H](F)[[email protected]@H](F)[[email protected]]3O)=C1
Purity	99.05%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.