Cat. No.: IBDP-531574
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Online InquiryTarget Information
Sequence Similarities | Belongs to the Bcl-2 family. |
Cellular Localization | Mitochondrion and Endomembrane system. Associated with intracytoplasmic membranes. |
Tissue Specificity | Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are ubiquitously expressed with a tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney. |
Function | Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis. |
Product Details
Product Type | Peptide |
Protein Length | Peptide |
Animal free | No |
Nature | Synthetic |
Application | BL |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at -20 °C. |
Handling | Avoid freeze / thaw cycle. |