BLK-IN-2

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Cat. No.: IBDI-435524

BLK-IN-2 (compound 25) is a potent and selective irreversible inhibitor of B-Lymphoid tyrosine kinase (BLK), with an IC50 of 5.9 nM. BLK-IN-2 also inhibits BTK (IC50=202.0 nM). BLK-IN-2 shows potent antiproliferative activities against several lymphoma cells.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	Btk
Molecular Weight	683.80
Appearance	Solid
SMILES	O=C(C1=CC2=C(C=NC=C2)C=C1)NC3=CC=C(C)C(C(NC4=CN=C(NC5=CC=CC(NC6CCN(C(/C=C/CN(C)C)=O)CC6)=C5)N=C4)=O)=C3
Purity	98.72%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.