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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

BQ-123

Cat. No.: IBDI-435952

BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC50 of 7.3 nM and a Ki of 25 nM. BQ-123 inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells and lowers blood pressure in different rat models of hypertension.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target Endothelin Receptor
Molecular Weight 610.70
Appearance Solid
SMILES O=C(N[[email protected]](C(N(CCC1)[[email protected]]1([H])C2=O)=O)([H])CC(O)=O)[[email protected]](NC([[email protected]@H](NC([[email protected]](N2)C(C)C)=O)CC(C)C)=O)CC3=CNC4=CC=CC=C34
Purity 99.44%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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