c-di-AMP diammonium

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Cat. No.: IBDI-434684

c-di-AMP diammonium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP diammonium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP diammonium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses.

Size (Solid):

Product Details

Target	STING \| Bacterial \| Endogenous Metabolite
Molecular Weight	692.47
Appearance	Solid
Synonyms	Cyclic diadenylate diammonium, Cyclic-di-AMP diammonium
SMILES	O[[email protected]]([[email protected]@](OP(O)(OC[[email protected]](O[[email protected]@H](N1C2=NC=NC(N)=C2N=C1)[[email protected]@H]3O)([H])[[email protected]@]3([H])O4)=O)([H])[[email protected]](COP4(O)=O)([H])O5)[[email protected]@H]5N6C7=NC=NC(N)=C7N=C6.N.N
Purity	98.81%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.