c-di-AMP disodium

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Cat. No.: IBDI-434686

c-di-AMP (Cyclic diadenylate) sodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP sodium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP sodium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses.

Size (Solid):

Product Details

Target	STING \| Bacterial \| Endogenous Metabolite
Molecular Weight	702.38
Appearance	Solid
Synonyms	Cyclic diadenylate disodium, Cyclic-di-AMP disodium
SMILES	O[[email protected]]([[email protected]@](OP(OC[[email protected]](O[[email protected]@H](N1C2=NC=NC(N)=C2N=C1)[[email protected]@H]3O)([H])[[email protected]@]3([H])O4)(O[Na])=O)([H])[[email protected]](COP4(O[Na])=O)([H])O5)[[email protected]@H]5N6C7=NC=NC(N)=C7N=C6
Purity	99.53%

Storage & Handling

Shipping	Shipping with dry ice.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.