c-di-AMP

Cat. No.: IBDI-434685

c-di-AMP (Cyclic diadenylate) is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP (Cyclic diadenylate) is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP (Cyclic diadenylate) acts as a potent mucosal adjuvant stimulating both humoral and cellular responses.

Product Details

Target	STING | Bacterial | Endogenous Metabolite
Molecular Weight	658.41
Appearance	Solid
Synonyms	Cyclic diadenylate, Cyclic-di-AMP
SMILES	O[[email protected]]([[email protected]@](OP(O)(OC[[email protected]](O[[email protected]@H](N1C2=NC=NC(N)=C2N=C1)[[email protected]@H]3O)([H])[[email protected]@]3([H])O4)=O)([H])[[email protected]](COP4(O)=O)([H])O5)[[email protected]@H]5N6C7=NC=NC(N)=C7N=C6

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.