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c-Jun Monoclonal Antibody - BSA and Azide Free

Cat. No.: IBDA-434740

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Target Information

Target Name c-Jun
Uniprot ID P05412
Cellular Localization Nucleus.
Immunogen Recombinant fragment.
Function Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).

Product Details

Description Mouse monoclonal antibody to c-Jun - BSA and Azide Free.
Host Species Mouse
Clonality Monoclonal
Purity Protein A purified
Isotype IgG2a
Conjugation Unconjugated
Reactivity Mouse, Rat, Human
Immunogen Recombinant fragment.
Positive Control WB: HEK-293, HeLa, NIH/3T3. PC-12 and MDA-MB-231 whole cell lysate.
IHC-P: Human esophagus and colon tissue. Mouse and rat hippocampus tissue. Mouse and rat cerebrum tissue.
ICC/IF: MDA-MB-231 cells.
Application ICC/IF, IHC-P, WB

Storage & Handling

Shipping Shipped at 4 °C.
Storage Store at 4 °C
Storage Buffer Constituent: 100% PBS
Handling Do not freeze.
! For research use only, not intended for any clinical use.