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c-Jun Monoclonal Antibody

Cat. No.: IBDA-434730

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Target Information

Target Name c-Jun
Uniprot ID P05412
Cellular Localization Nucleus.
Immunogen Synthetic peptide.
Function Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).

Product Details

Description HRP Rabbit monoclonal antibody to c-Jun.
Host Species Rabbit
Clonality Monoclonal
Purity Protein A purified
Isotype IgG
Conjugation HRP
Reactivity Mouse
Immunogen Synthetic peptide.
Positive Control WB: NIH 3T3 cell lysate.
Application WB

Storage & Handling

Shipping Shipped at 4 °C.
Storage Upon delivery aliquot. Store at -20 °C
Storage Buffer pH: 7.40
Preservative: 0.1% Proclin 300 Solution
Constituent: 30% Glycerol, 1% BSA, PBS
Handling Avoid freeze-thaw cycles.
! For research use only, not intended for any clinical use.