Cat. No.: IBDA-434751
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Online InquiryTarget Information
| Target Name | c-Jun |
| Uniprot ID | P05412 |
| Cellular Localization | Nucleus. |
| Immunogen | Recombinant fragment. |
| Function | Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306). |
Product Details
| Description | Mouse monoclonal antibody to c-Jun. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Rat, Human |
| Immunogen | Recombinant fragment. |
| Positive Control | WB: HEK-293, HeLa, NIH/3T3. PC-12 and MDA-MB-231 whole cell lysate. IHC-P: Human esophagus and colon tissue. Mouse and rat hippocampus tissue. Mouse and rat cerebrum tissue. ICC/IF: MDA-MB-231 cells. |
| Application | ICC/IF, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | Preservative: 0.01% Sodium Azide Constituent: 40% Glycerol, 0.05% BSA, 59% PBS |
| Handling | Avoid freeze-thaw cycles. |