Cat. No.: IBDA-434729
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Online InquiryTarget Information
| Target Name | c-Jun |
| Uniprot ID | P05412 |
| Cellular Localization | Nucleus. |
| Immunogen | Synthetic peptide. |
| Function | Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306). |
Product Details
| Description | Rabbit monoclonal antibody to c-Jun. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Affinity purified |
| Isotype | IgG |
| Conjugation | Alexa Fluor® 488 |
| Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Positive Control | ICC/IF: SW480 cells. ICC/IF KO: HEK293 cells (HEK293-JUN KO used as a negative cell line) |
| Application | ICC/IF |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C. Store in the dark |
| Storage Buffer | pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: 30% Glycerol, 1% BSA, PBS |
| Handling | Avoid freeze-thaw cycles. |