Cat. No.: IBDA-434748
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Online InquiryTarget Information
| Target Name | c-Jun (phospho S63) |
| Uniprot ID | P05412 |
| Cellular Localization | Nucleus. |
| Immunogen | Synthetic peptide within Human c-Jun aa 50-150 (phospho S63). |
| Function | Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306). |
Product Details
| Description | Rabbit monoclonal antibody to c-Jun (phospho S63). |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Human |
| Immunogen | Synthetic peptide within Human c-Jun aa 50-150 (phospho S63). |
| Positive Control | WB: UV or Anisomycin treated NIH/3T3 or HeLa whole cell lysate. IHC-P: Human breast carcinoma tissue. ICC/IF: A431 cells, NIH/3T3 cells. |
| Application | Dot, ELISA, ICC/IF, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.01% Sodium Azide Constituent: 59% PBS, 40% Glycerol, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |