C3/C3b Monoclonal Antibody

Target Information

Target Name	C3/C3b
Uniprot ID	P01024
Cellular Localization	Secreted.
Immunogen	The details of the immunogen for this antibody are not available.
Function	C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Product Details

Description	Mouse monoclonal antibody to C3 / C3b.
Host Species	Mouse
Clonality	Monoclonal
Purity	Tissue culture supernatant
Isotype	IgM
Conjugation	Unconjugated
Reactivity	Rat
Immunogen	The details of the immunogen for this antibody are not available.
Application	ELISA, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Upon delivery aliquot. Store at -20 °C
Storage Buffer	Preservative: 0.02% Sodium Azide Constituent: Tissue Culture Supernatant
Handling	Avoid freeze-thaw cycles.