Cat. No.: IBDA-435119
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Online InquiryTarget Information
| Target Name | C3/C3b |
| Uniprot ID | P01024 |
| Cellular Localization | Secreted. |
| Immunogen | Synthetic peptide corresponding to Human C3/ C3b aa 1300 to the C-terminus. |
| Function | C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. |
Product Details
| Description | Mouse monoclonal antibody to C3 / C3b. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein G purified |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Reactivity | Human, Cynomolgus monkey |
| Immunogen | Synthetic peptide corresponding to Human C3/ C3b aa 1300 to the C-terminus. |
| Application | ICC/IF, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Upon delivery aliquot. Store at -20 °C |
| Storage Buffer | Preservative: 0.02% Sodium Azide Constituent: PBS, 0.1% BSA |
| Handling | Avoid freeze-thaw cycles. |