C5 Monoclonal Antibody - BSA and Azide Free

Target Information

Target Name	C5
Uniprot ID	P01031
Cellular Localization	Secreted.
Immunogen	Recombinant fragment.
Function	Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis).

Product Details

Description	Rabbit monoclonal antibody to C5 - BSA and Azide Free (Detector).
Host Species	Rabbit
Clonality	Monoclonal
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Recombinant fragment.
Application	sELISA

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	pH: 7.2 Constituent: 100% PBS