Camptothecin-d5

Cat. No.: IBDI-431644

Camptothecin-d5 is the deuterium labeled Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells.

Product Details

Target	TopoisomeRase | ADC Cytotoxin | MicroRNA | Influenza Virus | Apoptosis | Fungal | Antibiotic
Molecular Weight	353.38
Synonyms	Campathecin-d5, (S)-(+)-Camptothecin-d5, CPT-d5
SMILES	[2H]C([2H])([2H])C([2H])([2H])[[email protected]@]1(C2=C(COC1=O)C(N3C(C4=NC5=CC=CC=C5C=C4C3)=C2)=O)O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.