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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Carfilzomib

Cat. No.: IBDI-432236

Carfilzomib (PR-171) is an irreversible proteasome inhibitor with an IC50 of 5 nM in ANBL-6 and RPMI 8226 cells.

Size (Solid):

Product Details

Target Proteasome | Autophagy | Apoptosis
Molecular Weight 719.91
Appearance Solid
Synonyms PR-171
SMILES C[[email protected]@]1(C([[email protected]](CC(C)C)NC([[email protected]@H](NC([[email protected]](CC(C)C)NC([[email protected]@H](NC(CN2CCOCC2)=O)CCC3=CC=CC=C3)=O)=O)CC4=CC=CC=C4)=O)=O)OC1
Purity 99.46%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
*The compound is unstable in solutions, freshly prepared is recommended.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.