Cbl-b-IN-3

Cat. No.: IBDI-433586

Cbl-b-IN-3 (Compound 23) is a casitas B-lineage lymphoma proto-oncogene-b (Cbl-b) inhibitor with an IC50 of < 1 nM. Cbl-b is an E3 ubiquitin ligase that negatively regulates T-cell activation.

Product Details

Target	E1/E2/E3 Enzyme
Molecular Weight	537.62
Appearance	Solid
SMILES	CN1C([[email protected]@]2(C3=CC(N4CC5=C(C(F)(F)F)C=C(CN6C[[email protected]](CCC6)C)C=C5C4=O)=CC=C3)C[[email protected]](C2)C)=NN=C1
Purity	99.42%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.