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CBP/p300-IN-12

Cat. No.: IBDI-432459

CBP/p300-IN-12 is a potent and selective covalent histone acetyltransferases p300 (IC50 of 166 nM) and CBP inhibitor. CBP/p300-IN-12 decreases the levels of H3K27Ac of PC-3 cells (EC50 of 37 nM). CBP/p300-IN-12 forms a covalent adduct with C1450.

Size (Solid):

Product Details

Target Epigenetic Reader Domain | Histone AcetyltransfeRase
Molecular Weight 667.61
Appearance Solid
SMILES C=CC(NC1=CC=CC(NC(NC2=CC3=C([[email protected]]4(OC(N(CC(N(CC5=CC=C(F)C=C5)[[email protected]@H](C)C(F)(F)F)=O)C4=O)=O)CC3)C=C2)=O)=C1)=O
Purity 99.70%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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