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CC-90005

Cat. No.: IBDI-434273

CC-90005 is a potent, selective and orally active inhibitor of protein kinase C-θ (PKC-θ), with an IC50 of 8 nM. CC-90005 shows selectivity for PKC-θ over PKC-δ (IC50=4440 nM). CC-90005 can inhibit T cell activation by inhibiting IL-2 expression.

Size (Solid):

Product Details

Target PKC
Molecular Weight 447.48
Appearance Solid
SMILES N#CC1=CN=C(NCC2=CN=CN=C2OCC(F)(F)C)N=C1N[[email protected]]3CC(C)(C)[[email protected]@H](O)CC3
Purity 99.98%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.