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CCR2 antagonist 4 hydrochloride

Cat. No.: IBDI-431514

CCR2 antagonist 4 hydrochloride (Teijin compound 1 hydrochloride) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 hydrochloride potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM.

Size (Solid):

Product Details

Target CCR
Molecular Weight 476.32
Appearance Solid
Synonyms Teijin compound 1 hydrochloride
SMILES O=C(NCC(N[[email protected]]1CN(CC2=CC=C(Cl)C=C2)CC1)=O)C3=CC=CC(C(F)(F)F)=C3.[H]Cl
Purity 99.86%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage 4°C
*In solvent : -80°C, 6 months; -20°C, 1 month
Handling Sealed storage, away from moisture
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.