CCR2 antagonist 5

Cat. No.: IBDI-435803

CCR2 antagonist 5 is a selective, orally active hCCR2 inhibitor with good binding affinity (IC50=37 nM) and potent functional antagonism (chemotaxis IC50=30 nM). CCR2 antagonist 5 displays a Ki of 9.6 µM for mCCR2 binding. CCR2 antagonist 5 can be used in the research of inflammatory disease.

Product Details

Target	CCR
Molecular Weight	482.52
SMILES	O=C(CNC(C1=CC(C(F)(F)F)=CC=C1)=O)NC2CN(C2)[[email protected]](CC3)([H])CC[[email protected]@]3(C4=CN=CS4)O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.