Cat. No.: IBDA-432512
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Online InquiryTarget Information
| Target Name | CCR3 |
| Uniprot ID | P51677 |
| Cellular Localization | Cell membrane. |
| Immunogen | Synthetic peptide: TDEIKTVVESFETTPYEYEWAPPC , corresponding to N terminal amino acids 5-29 of Mouse CCR3. |
| Function | Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. |
Product Details
| Description | Goat polyclonal antibody to CCR3. |
| Host Species | Goat |
| Clonality | Polyclonal |
| Purity | Protein G purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse |
| Immunogen | Synthetic peptide: TDEIKTVVESFETTPYEYEWAPPC , corresponding to N terminal amino acids 5-29 of Mouse CCR3. |
| Positive Control | Human spleen sections or cytosmears/cytospins of human peripheral blood leukocytes. A549 cell line also has been shown to express CCR3 receptor. |
| Application | IHC-P |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Upon delivery aliquot. Store at -20 °C or -80 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.1% Sodium Azide Constituent: 0.21% Potassium Phosphate, 0.812% Sodium Chloride, 0.1% BSA |
| Handling | Avoid freeze-thaw cycles. |