Cat. No.: IBDA-432496
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Online InquiryTarget Information
Target Name | CCR4 |
Uniprot ID | P51679 |
Cellular Localization | Cell membrane. |
Immunogen | Synthetic peptide. |
Function | High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. |
Product Details
Description | Rabbit monoclonal antibody to CCR4 - BSA and Azide Free. |
Host Species | Rabbit |
Clonality | Monoclonal |
Purity | Protein A purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Synthetic peptide. |
Positive Control | Flow Cyt: HDLM-2, and PBMC cells. HEK-293T cells transfected with GFP tagged CCR4 overexpression vector. |
Application | Flo |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C |
Storage Buffer | Constituent: 100% PBS |