Cat. No.: IBDA-432494
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Online InquiryTarget Information
| Target Name | CCR4 |
| Uniprot ID | P51679 |
| Cellular Localization | Cell membrane. |
| Immunogen | Synthetic peptide. |
| Function | High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. |
Product Details
| Description | Rabbit monoclonal antibody to CCR4. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Alexa Fluor® 647 |
| Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Positive Control | Flow Cyt: Human peripheral blood mononuclear cells (PBMCs). |
| Application | Flo |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C. Store in the dark |
| Storage Buffer | pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: 30% Glycerol, 1% BSA, 68% PBS |
| Handling | Avoid freeze-thaw cycles. |