CCR4 Monoclonal Antibody

Target Information

Target Name	CCR4
Uniprot ID	P51679
Cellular Localization	Cell membrane.
Immunogen	Synthetic peptide from human CCR4.
Function	High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.

Product Details

Description	Mouse monoclonal antibody to CCR4.
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein G purified
Isotype	IgG2a
Conjugation	Unconjugated
Reactivity	Recombinant fragment
Immunogen	Synthetic peptide from human CCR4.
Application	Flo, ICC/IF

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.20 Constituent: PBS
Handling	Avoid freeze-thaw cycles.