Cat. No.: IBDA-432495
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Online InquiryTarget Information
Target Name | CCR4 |
Uniprot ID | P51679 |
Cellular Localization | Cell membrane. |
Immunogen | Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Mouse CCR4. |
Function | High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. |
Product Details
Description | Rabbit polyclonal antibody to CCR4. |
Host Species | Rabbit |
Clonality | Polyclonal |
Purity | Immunogen affinity purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Mouse |
Immunogen | Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Mouse CCR4. |
Positive Control | This antibody gave a positive signal in the following Mouse lysates: Thymus Tissue, Spleen Tissue and RAW 264.7 Whole Cell. |
Application | WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Short term: 4 °C. Long term: -20 °C |
Storage Buffer | pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: PBS |
Handling | Avoid freeze-thaw cycles. |