Cat. No.: IBDA-432497
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Online InquiryTarget Information
| Target Name | CCR4 |
| Uniprot ID | P51679 |
| Cellular Localization | Cell membrane. |
| Immunogen | Synthetic peptide within Human CCR4 aa 200-300 conjugated to keyhole limpet haemocyanin. |
| Function | High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. |
Product Details
| Description | Rabbit polyclonal antibody to CCR4. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Rat |
| Immunogen | Synthetic peptide within Human CCR4 aa 200-300 conjugated to keyhole limpet haemocyanin. |
| Application | WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.09% Sodium Azide Constituent: 1% BSA, 50% Glycerol |
| Handling | Avoid freeze-thaw cycles. |