Cat. No.: IBDA-432491
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Online InquiryTarget Information
| Target Name | CCR5 |
| Uniprot ID | P51681 |
| Cellular Localization | Cell membrane. |
| Immunogen | Synthetic peptide. |
| Function | Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates. |
Product Details
| Description | Rabbit monoclonal antibody to CCR5. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Positive Control | Flow Cyt (Intra): Human PBMC cells. Human PBMC cells treated with 50 ng/ml PMA and 500 ng/ml lonomycin for 24 hours. |
| Application | Flo |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | Preservative: 0.01% Sodium Azide Constituent: 59.94% PBS, 40% Glycerol, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |