CD130 (gp130) Monoclonal Antibody

Target Information

Target Name	CD130 (gp130)
Uniprot ID	P40189
Cellular Localization	Secreted and Cell membrane.
Immunogen	Recombinant fragment.
Function	Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development (By similarity). The type I OSM receptor is capable of transducing OSM-specific signaling events.

Product Details

Description	Rabbit monoclonal antibody to CD130 (gp130).
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse, Rat, Human
Immunogen	Recombinant fragment.
Positive Control	WB: Wild-type A549, PC-3, Daudi, HepG2, MG-63, NIH/3T3, MEF, C6, Untreated NIH/3T3 and NIH/3T3 treated with PNGase F whole cell lysate. Mouse thymus and lung tissue lysate. IP: NIH/3T3 cells.
Application	IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: 59% PBS, 40% Glycerol, 0.05% BSA
Handling	Avoid freeze-thaw cycles.