CD130 (gp130) Monoclonal Antibody

Target Information

Target Name	CD130 (gp130)
Uniprot ID	P40189
Cellular Localization	Secreted and Cell membrane.
Immunogen	Natural soluble gp130 receptor (Human).
Function	Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development (By similarity). The type I OSM receptor is capable of transducing OSM-specific signaling events.

Product Details

Description	Mouse monoclonal antibody to CD130 (gp130).
Host Species	Mouse
Clonality	Monoclonal
Purity	Ion Exchange Chromatography
Isotype	IgG1
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Natural soluble gp130 receptor (Human).
Application	ELISA, Flo

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	Preservative: 0.09% Sodium Azide Constituent: PBS
Handling	Avoid freeze-thaw cycles.