Cat. No.: IBDA-432758
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Online InquiryTarget Information
| Target Name | CD130 (gp130) |
| Uniprot ID | P40189 |
| Cellular Localization | Secreted and Cell membrane. |
| Immunogen | Recombinant fragment within Human CD130 (gp130) (C terminal). |
| Function | Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development (By similarity). The type I OSM receptor is capable of transducing OSM-specific signaling events. |
Product Details
| Description | Rabbit polyclonal antibody to CD130 (gp130) - C-terminal. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment within Human CD130 (gp130) (C terminal). |
| Positive Control | WB: HepG2 whole cell lysate. IHC-P: J5 xenograft tissue. ICC/IF: HeLa cells. |
| Application | ICC/IF, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7 Preservative: 0.025% Proclin 300 Constituent: 78% PBS, 1% BSA, 20% Glycerol |
| Handling | Avoid freeze-thaw cycles. |