Cat. No.: IBDA-432766
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Online InquiryTarget Information
Target Name | CD130 (gp130) |
Uniprot ID | P40189 |
Cellular Localization | Secreted and Cell membrane. |
Immunogen | Synthetic peptide within Mouse CD130 (gp130) aa 650-750 conjugated to keyhole limpet haemocyanin. |
Function | Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development (By similarity). The type I OSM receptor is capable of transducing OSM-specific signaling events. |
Product Details
Description | Rabbit polyclonal antibody to CD130 (gp130). |
Host Species | Rabbit |
Clonality | Polyclonal |
Purity | Protein A purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Mouse, Rat |
Immunogen | Synthetic peptide within Mouse CD130 (gp130) aa 650-750 conjugated to keyhole limpet haemocyanin. |
Positive Control | IHC-P: Mouse and Rat Adrenal gland tissue |
Application | IHC-P |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Short term: 4 °C. Long term: -20 °C |
Storage Buffer | pH: 7.2 Preservative: 0.09% Sodium Azide Constituent: 50% Glycerol, 0.01% BSA |
Handling | Avoid freeze-thaw cycles. |