CD14 Monoclonal Antibody

Target Information

Target Name	CD14
Uniprot ID	P08571
Cellular Localization	Cell membrane.
Immunogen	Recombinant fragment corresponding to Human CD14 aa 20-214.
Function	Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.

Product Details

Description	Mouse monoclonal antibody to CD14.
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein G purified
Isotype	IgG2a
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Recombinant fragment corresponding to Human CD14 aa 20-214.
Positive Control	WB: Human CD14 (aa 20-214) recombinant protein. CD14 (aa 20-214)-hIgGFc transfected HEK-293 cell lysate. IHC-P: Human cervical cancer and colon tissues. ICC/IF: HepG2 cells.
Application	ICC/IF, IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	Preservative: 0.05% Sodium Azide Constituent: PBS
Handling	Avoid freeze-thaw cycles.