Cat. No.: IBDA-434474
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Online InquiryTarget Information
| Target Name | CD14 |
| Uniprot ID | P08571 |
| Cellular Localization | Cell membrane. |
| Immunogen | Synthetic peptide. |
| Function | Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. |
Product Details
| Description | Rabbit monoclonal antibody to CD14. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Alexa Fluor® 647 |
| Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Positive Control | IHC-P: Human tonsil and lung carcinoma FFPE tissue sections. Flow Cyt: Human peripheral blood mononuclear cell (PBMC). |
| Application | Flo, IHC-P |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C. Store in the dark |
| Storage Buffer | pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: 68% PBS, 30% Glycerol, 1% BSA |
| Handling | Avoid freeze-thaw cycles. |