Cat. No.: IBDA-434507
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Online InquiryTarget Information
| Target Name | CD14 |
| Uniprot ID | P08571 |
| Cellular Localization | Cell membrane. |
| Immunogen | Recombinant fragment within Human CD14 aa 25-148. |
| Function | Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. |
Product Details
| Description | Mouse monoclonal antibody to CD14. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein A/G purified |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment within Human CD14 aa 25-148. |
| Positive Control | IHC-P: Human lymph node and tonsil tissues. |
| Application | IHC-P |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.05% Sodium Azide Constituent: PBS, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |