Cat. No.: IBDA-434504
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Online InquiryTarget Information
Target Name | CD14 |
Uniprot ID | P08571 |
Cellular Localization | Cell membrane. |
Immunogen | Recombinant fragment corresponding to Human CD14 aa 1-150. |
Function | Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. |
Product Details
Description | Mouse monoclonal antibody to CD14. |
Host Species | Mouse |
Clonality | Monoclonal |
Purity | Protein A purified |
Isotype | IgG1 |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Recombinant fragment corresponding to Human CD14 aa 1-150. |
Positive Control | IHC-P: Human liver, tonsil and rectum tissue. |
Application | IHC-P |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Short term: 4 °C. Long term: -20 °C |
Storage Buffer | pH: 7.20 Preservative: 0.02% Sodium Azide Constituent: 40% Glycerol, PBS |
Handling | Avoid freeze-thaw cycles. |