CD14 Monoclonal Antibody

Target Information

Target Name	CD14
Uniprot ID	P08571
Cellular Localization	Cell membrane.
Immunogen	Recombinant fragment corresponding to Human CD14 aa 1-250.
Function	Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.

Product Details

Description	Mouse monoclonal antibody to CD14.
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein G purified
Isotype	IgG1
Conjugation	Unconjugated
Reactivity	Mouse, Human
Immunogen	Recombinant fragment corresponding to Human CD14 aa 1-250.
Positive Control	Human CD14 recombinant protein (amino acids 20-214), lysate from HEK293 cells transfected with CD14 (amino acids 20-214)-hIgGFc, HepG2, A549, HL60, mouse RAW264.7, Hela, HEK293 and mouse NIH 3T3 cell lysates. Jurkat cells. Human stomach cancer tissue.
Application	Flo, IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	Preservative: 0.05% Sodium Azide Constituent: 99% PBS
Handling	Avoid freeze-thaw cycles.