Cat. No.: IBDA-434475
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Online InquiryTarget Information
Target Name | CD14 |
Uniprot ID | P08571 |
Cellular Localization | Cell membrane. |
Immunogen | A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria. |
Function | Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. |
Product Details
Description | APC Mouse monoclonal antibody to CD14. |
Host Species | Mouse |
Clonality | Monoclonal |
Purity | Size exclusion |
Isotype | IgG1 |
Conjugation | APC |
Reactivity | Human |
Immunogen | A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria. |
Positive Control | Human blood cells |
Application | Flo |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C |
Storage Buffer | pH: 7.4 Preservative: 0.097% Sodium Azide Constituent: 1% BSA |