Cat. No.: IBDA-434496
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Online InquiryTarget Information
Target Name | CD14 |
Uniprot ID | P08571 |
Cellular Localization | Cell membrane. |
Immunogen | Recombinant fragment, corresponding to amino acids 25-285 of Human CD14 (BC010507). |
Function | Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. |
Product Details
Description | Rabbit polyclonal antibody to CD14. |
Host Species | Rabbit |
Clonality | Polyclonal |
Purity | Immunogen affinity purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Recombinant fragment, corresponding to amino acids 25-285 of Human CD14 (BC010507). |
Positive Control | Human fetal thymus and Hep2 cell lysates |
Application | WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at -20 °C |
Storage Buffer | Preservative: 0.02% Sodium Azide Constituent: 1% BSA |
Handling | Avoid freeze-thaw cycles. |