Cat. No.: IBDA-432657
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Online InquiryTarget Information
| Target Name | CD146 |
| Uniprot ID | P43121 |
| Cellular Localization | Membrane. |
| Immunogen | Tissue, cells or virus corresponding to Human CD146. |
| Function | Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration. |
Product Details
| Description | PE Mouse monoclonal antibody to CD146. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Size exclusion |
| Isotype | IgG1 |
| Conjugation | PE |
| Reactivity | Human |
| Immunogen | Tissue, cells or virus corresponding to Human CD146. |
| Positive Control | Flow Cyt: HUVEC cells. |
| Application | Flo |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C. Store in the dark |
| Storage Buffer | pH: 7.4 Preservative: 0.0975% Sodium Azide Constituent: PBS |
| Handling | Do not freeze. |