Cat. No.: IBDA-432652
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Online InquiryTarget Information
| Target Name | CD146 |
| Uniprot ID | P43121 |
| Cellular Localization | Membrane. |
| Immunogen | Recombinant fragment corresponding to Human CD146 aa 1-600. |
| Function | Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration. |
Product Details
| Description | APC Mouse monoclonal antibody to CD146. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG1 |
| Conjugation | APC |
| Reactivity | Human |
| Immunogen | Recombinant fragment corresponding to Human CD146 aa 1-600. |
| Positive Control | Flow Cyt: HeLa cells. |
| Application | Flo |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C. Store in the dark |
| Storage Buffer | Preservative: 0.09% Sodium Azide Constituent: 0.5% BSA |
| Handling | Do not freeze. |