CD147 Monoclonal Antibody

Target Information

Target Name	CD147
Uniprot ID	P35613
Cellular Localization	Cell membrane. Melanosome. Colocalizes with SLC16A1 and SLC16A8 (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Immunogen	Recombinant fragment.
Function	Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.

Product Details

Description	Rabbit monoclonal antibody to CD147.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse
Immunogen	Recombinant fragment.
Positive Control	WB: His-tagged mouse CD147 recombinant protein fragment (aa140-325). RAW 264.7, WEHI-3 and bEND.3 whole cell lysates. Mouse liver lysate. IHC-P: Mouse intestine tissue. ICC/IF: bEnd.3 and WEHI-231 cells. Flow Cyt: Mouse thymocytes. IP: RAW 264.7 whole cell lysate.
Application	Flo, ICC/IF, IHC-P, IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: 0.05% BSA, 40% Glycerol, PBS
Handling	Avoid freeze-thaw cycles.