CD147 Monoclonal Antibody

Target Information

Target Name	CD147
Uniprot ID	P35613
Cellular Localization	Cell membrane. Melanosome. Colocalizes with SLC16A1 and SLC16A8 (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Immunogen	Protein A-CR purified soluble recombinant Human CD147 (consisting of the CDNA encoding the hinge region, CH2-and CH3 domain of Human IgG1).
Function	Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.

Product Details

Description	Mouse monoclonal antibody to CD147 - Low Endotoxin, Azide Free.
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG1
Conjugation	Unconjugated
Reactivity	Human, Simian Virus 40
Immunogen	Protein A-CR purified soluble recombinant Human CD147 (consisting of the CDNA encoding the hinge region, CH2-and CH3 domain of Human IgG1).
Positive Control	Flow Cyt: Human peripheral blood lymphocytes ICC/IF: SV40 cells.
Application	Flo, ICC/IF

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Upon delivery aliquot. Store at -20 °C
Storage Buffer	pH: 7.40 Constituent: 99% PBS
Handling	Avoid freeze-thaw cycles.