CD147 Monoclonal Antibody

Target Information

Target Name	CD147
Uniprot ID	P35613
Cellular Localization	Cell membrane. Melanosome. Colocalizes with SLC16A1 and SLC16A8 (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Immunogen	Recombinant full length protein (Human): Protein A CR purified soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the hinge region, CH2 and CH3 domain of human IgG1 (CD147Rg is secreted by transfectants as a dimmer).
Function	Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.

Product Details

Description	Biotin Mouse monoclonal antibody to CD147.
Host Species	Mouse
Clonality	Monoclonal
Purity	Protein G purified
Isotype	IgG1
Conjugation	Biotin
Reactivity	Human
Immunogen	Recombinant full length protein (Human): Protein A CR purified soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the hinge region, CH2 and CH3 domain of human IgG1 (CD147Rg is secreted by transfectants as a dimmer).
Positive Control	Flow Cyt: human peripheral blood
Application	Flo, IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.40 Preservative: 0.097% Sodium Azide Constituent: PBS
Handling	Avoid freeze-thaw cycles.