Cat. No.: IBDA-432807
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Online InquiryTarget Information
| Target Name | CD147 |
| Uniprot ID | P35613 |
| Cellular Localization | Cell membrane. Melanosome. Colocalizes with SLC16A1 and SLC16A8 (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Immunogen | Recombinant fragment (His-T7-tag) corresponding to Rat CD147 aa 50-350. |
| Function | Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes. |
Product Details
| Description | Rabbit polyclonal antibody to CD147. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Rat |
| Immunogen | Recombinant fragment (His-T7-tag) corresponding to Rat CD147 aa 50-350. |
| Positive Control | WB: Recombinant rat CD147 protein. Rat liver lysate. IHC-P: Rat liver, pancreas, stomach and heart tissues. |
| Application | IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: PBS, 50% Glycerol |
| Handling | Avoid freeze-thaw cycles. |