Cat. No.: IBDA-434835
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Online InquiryTarget Information
Target Name | CD18 |
Uniprot ID | P05107 |
Cellular Localization | Membrane. |
Immunogen | Recombinant fragment. |
Function | Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. |
Product Details
Description | Rabbit monoclonal antibody to CD18 - BSA and Azide Free. |
Host Species | Rabbit |
Clonality | Monoclonal |
Purity | Protein A purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Recombinant fragment. |
Positive Control | WB: Human lymphoma tissue lysate. U-937 whole cell lysate. IHC-P: Human spleen and lung tissue. HEK-293T transformed with a ITGB2 expression vector containing his tag. ICC/IF: U-937 cells. Flow Cyt: Human peripheral blood mononuclear cell (PBMC). U-937 cells. |
Application | Flo, ICC/IF, IHC-P, WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C |
Storage Buffer | pH: 7.2 Constituent: 100% PBS |