CD18 Monoclonal Antibody

Target Information

Target Name	CD18
Uniprot ID	P05107
Cellular Localization	Membrane.
Immunogen	Recombinant fragment.
Function	Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1.

Product Details

Description	Rabbit monoclonal antibody to CD18.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Recombinant fragment.
Positive Control	WB: Human lymphoma tissue lysate. U-937 whole cell lysate. IHC-P: Human spleen and lung tissue. HEK-293T transformed with a ITGB2 expression vector containing his tag. ICC/IF: U-937 cells. Flow Cyt: Human peripheral blood mononuclear cell (PBMC). U-937 cells.
Application	Flo, ICC/IF, IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: 40% Glycerol, 0.05% BSA, 59% PBS
Handling	Avoid freeze-thaw cycles.