Cat. No.: IBDA-434838
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Online InquiryTarget Information
| Target Name | CD18 (phospho S745) |
| Uniprot ID | P05107 |
| Cellular Localization | Membrane. |
| Immunogen | Synthetic peptide within Human CD18 (phospho S745). |
| Function | Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. |
Product Details
| Description | Rabbit monoclonal antibody to CD18 (phospho S745). |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Rat, Human |
| Immunogen | Synthetic peptide within Human CD18 (phospho S745). |
| Positive Control | WB: Jurkat, NIH/3T3 and PC-12 cell lysate This antibody gave a positive result when used in the following formaldehyde fixed cell lines: Raw 246.7 |
| Application | IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.01% Sodium Azide Constituent: 59% PBS, 40% Glycerol, 0.5% BSA |
| Handling | Avoid freeze-thaw cycles. |